In a recent study by the CDC, both the Pfizer and Moderna COVID-19 vaccines demonstrated remarkable effectiveness in preventing infections under real-world conditions, reducing the risk of infection by an impressive 90% two weeks after the second dose. This study, which focused on healthcare workers and first responders, provides much-needed reassurance after a challenging year of the pandemic.
The findings indicate that these vaccines are adept at preventing both symptomatic and asymptomatic infections, a significant consideration since clinical trial results can differ from real-life efficacy. One dose of the vaccine led to an 80% reduction in infections by the two-week mark, while the second dose increased this effectiveness to 90%. This is particularly encouraging, given ongoing discussions in the scientific community regarding the potential for vaccinated individuals to transmit the virus asymptomatically.
Additionally, the study evaluated the vaccines’ performance against emerging COVID-19 variants during a period from December 14, 2020, to March 13, 2021, and found that their efficacy remained robust despite the presence of these variants.
The research involved 3,950 participants at high risk for virus exposure, including frontline healthcare workers. Remarkably, none of the participants had prior COVID-19 infections. During the study, 62.8% received both vaccine doses, while 12.1% had received only one. Weekly self-collected nasal swabs allowed researchers to identify both symptomatic and asymptomatic infections. Notably, 58% of infections occurred before participants showed any symptoms, with only 10.2% of those infected remaining asymptomatic.
Among fully vaccinated participants, the infection rate was merely 0.04 per 1,000 person-days, which translates to just 0.04 infections daily for every 1,000 individuals. For those with only one shot, the infection rate was still reassuring at 0.19 per 1,000 person-days.
In summary, this study underscores the effectiveness of national vaccination efforts, as noted by CDC Director Dr. Rochelle P. Walensky.
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Summary
The CDC study reveals that Pfizer and Moderna vaccines are highly effective in real-world conditions, showing a 90% reduction in COVID-19 infections after two doses. This data provides reassurance about vaccine efficacy against both symptomatic and asymptomatic infections, even in the face of variants.
Keyphrase: Pfizer and Moderna vaccine effectiveness
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